The state Department of Health said Tuesday the most recent death occurred in Madison County. The first death was in Yazoo County.
Health officials also reported new human cases in Adams, Bolivar, Covington, Forrest and Rankin counties.
So far this year, a total of 15 human West Nile cases have been reported in the following counties: Adams (2), Bolivar (1), Covington (1), Forrest (1), Hinds (2), Madison (1), Newton (1), Rankin (4), Yazoo (1), and Wilkinson (1) counties.
The Health Department only reports laboratory-confirmed cases to the public. In 2013, Mississippi had 45 WNV cases and five deaths.