The state Department of Health said Monday that a Hinds County resident and a Rankin County resident have confirmed cases.
So far this year, nine cases of West Nile have been reported, including one death in Yazoo County.
Three people overall have been infected in Rankin County and two in Hinds County. One apiece has been infected in Adams, Newton, Yazoo and Wilkinson counties.
The Department of Health only reports laboratory-confirmed cases to the public.
In 2013, Mississippi had 45 confirmed West Nile cases and five deaths. In 2012, the state had 247 cases and five deaths.