The board voted 5-0 to approve the appointment.
Board President Dr. Bill Rogers said Cook, currently the assistant superintendent of the Pontotoc City School District, was chosen because the district is focused on academic excellence.
"Our top priority is academic excellence and we wanted a superintendent to get us to where we want to go - which is to be a star school district," Rogers said.
Rogers noted that Cook was one of the top three educators in the state with regards to the Common Core curriculum."
Departing superintendent Dr. Gearl Loden is set to taken the reins in the Tupelo School District at the beginning of the new school year. Dr. Rogers said Loden and Cook would work together to ensure a smooth transition. which would most likely occur on July 1.
Cook has been with the Pontotoc City School District since 2004.
Read more in Thursday's NEMS Daily Journal newspaper.