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Tipoff at Tad Smith Coliseum is set for 6 p.m., and the game will be seen on CSS.
The Ragin’ Cajuns (5-6) are in their second season under coach Bob Marlin, a Tupelo native.
Prior to accepting the La.-Lafayette job, Marlin was 225-131 at Sam Houston State in Huntsville, Texas. He led the Bearkats to the NCAA tournament twice and was named Southland Conference coach of the year three times.
The Cajuns are 0-4 on the road with losses at North Dakota State, San Francisco, Duquesne, Kent State and Lamar.
Junior forward Kadeem Coleby leads the team in scoring with 11.4 points a game. Senior forward Darshawn McClellan, a Vanderbilt transfer, has averaged 12.8 points over the last four games.
Ole Miss (7-1) is coming off an 80-56 win over Mississippi Valley State.
Murphy Holloway leads the Rebels in scoring (11.2 ppg) and rebounding (9.8 rpg). Holloway is seconds in the SEC and 26th nationally in rebounding.
Junior forward Reggie Buckner is averaging 2.9 blocked shots and needs two blocked shots to set the school record.
Sean Murphy is the current record-holder with 180 blocked shots from 1988-1991.