Winners will advance to North State, where a trip to the state championship is on the line in the best-of-three series.
Lafayette is at New Albany in Class 4A, while East Union visits Hatley in 2A and West Union goes to Tupelo Christian in 1A.
One softball series is still to be determined tonight. In Class 1A, Smithville hosts Pine Grove at 5 p.m. in Game 2 of that series. Smithville won the opener 16-2. Game 3 would follow. The winner faces Vardaman in the North State series.