The Mississippi Highway Patrol is handling the accident. Sgt. H.L. Kitchens said there were no fatalities in the accident.
According to Prentiss County Sheriff Randy Tolar his office received a call at 12:12 p.m. about an accident at the intersection of County Road 7000 and Highway 45.
At least one person involved in the accident had to be airlifted to medical care.
The accident is still under investigation.