Marshall County Coroner Richard Anderson said 9-year-old Roddrick L. Isom of Holly Springs was dead at the scene of the 7:40 a.m. collision roughly a half-mile north of Eddie Lee Smith Drive on State Highway 7.
"The bus was headed northbound, still running its route," said Lt. John Norman of the Holly Springs Police Department. A southbound Honda sedan apparently hit a patch of ice and skidded sideways into the path of the bus, he said.
The five surviving occupants of the car were taken by air and ground ambulance to Memphis-area hospitals.
The driver, 17-year-old LaTasha Isom, the victim's sister, was listed in serious condition at the Regional Medical Center at Memphis (The Med), which has the area's only Level 1 trauma center.
No information was available on the conditions of Gabrielle Byers, 15; Keyasha Jeffries, 15; R. L. Isom Jr., 13, brother of the victim and the driver; or Kirstin Byers, 9.
Asked about observations that the ice came from a broken water line, Norman said, "I have no idea. I just know there was ice on the road."
Police Chief Robert Pearson said students on the bus were checked by paramedics, but no significant injuries were apparent. Another bus took students on to their schools, where grief counselors were made available to those who wished to talk.
Holly Springs Superintendent of Education Irene Walton could not be reached for comment.
Contact reporter Errol Castens at (662) 281-1069 or firstname.lastname@example.org.